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    General information: [ref]

    Chloromycetin (Chloramphenicol)Chloramphenicol (trade names include Chloromycetin; Brochlor; Chemicetina; Chloramex; Chlorsig; Fenicol; Kemicetine; Levomycetin; Paraxin; Quemicetina; Synthomycine) is a broad-spectrum synthetic antibiotic and antiinfective medication for systemic, local and topical use from amphenicols pharmacological group. This medicine is used to treat various types bacterial and rickettsial infections such as eye, ear, skin, lung, blood, brain, gynecological infections, conjunctivitis, blepharitis, endophthalmitis, meningitis, brain abscesses, anthrax, brucellosis, glanders, Lemierre's syndrome, ornithosis, psittacosis, sepsis, acne, plague, cholera, fever, typhoid fever, Rocky Mountain spotted fever (RMSF), rabbit fever, purpura (petechial rash), vancomycin-resistant enterococcus, in veterinary medicine. Chloramphenicol works by killing or slowing the growth of sensitive bacteria.


    Pharmacological and medical categories:

  • Anti infective drugs
  • Antibacterials
  • Antibiotics
  • Chloramphenicols
  • Ear anti-infectives and antiseptics
  • Eye anti-infectives and antiseptics
  • Topical antiinfective preparations used in the treatment of acne
  • Veterinary, pet meds


    The Anatomical Therapeutic Chemical (ATC) classification system codes:

  • D - Dermatologicals
  • D06 - Antibiotics and chemotherapeutics for dermatological use
  • D06A - Antibiotics for topical use
  • D06AX - Other antibiotics for topical use
  • D06AX02 - Chloramphenicol

  • D10 - Anti-acne preparations
  • D10A - Anti-acne preparations for topical use
  • D10AF - Antiinfectives for treatment of acne
  • D10AF03 - Chloramphenicol

  • G - Genito urinary system and sex hormones
  • G01 - Gynecological antiinfectives and antiseptics
  • G01A - Antiinfectives and antiseptics, excl. combinations with corticosteroids
  • G01AA - Antibiotics
  • G01AA05 - Chloramphenicol

  • J - Antiinfectives for systemic use
  • J01 - Antibacterials for systemic use
  • J01B - Amphenicols
  • J01BA - Amphenicols
  • J01BA01 - Chloramphenicol

  • S - Sensory organs
  • S01 - Ophthalmologicals
  • S01A - Antiinfectives
  • S01AA - Antibiotics
  • S01AA01 - Chloramphenicol

  • S02 - Otologicals
  • S02A - Antiinfectives
  • S02AA - Antiinfectives
  • S02AA01 - Chloramphenicol

  • S03 - Ophthalmological and otological preparations
  • S03A - Antiinfectives
  • S03AA - Antiinfectives
  • S03AA08 - Chloramphenicol


    The International Statistical Classification of Diseases and Related Health Problems (ICD-10, World Health Organization) codes:

  • Cholera - A00
  • Typhoid and paratyphoid fevers - A01
  • Plague - A20
  • Tularemia - A21
  • Anthrax - A22
  • Brucellosis - A23
  • Glanders and melioidosis - A24
  • Streptococcal sepsis - A40
  • Other sepsis - A41
  • Chlamydia psittaci infections - A70
  • Spotted fever [tick-borne rickettsioses] - A77
  • Purpura and other hemorrhagic conditions - D69
  • Meningitis in bacterial diseases classified elsewhere - G01
  • Meningitis in other infectious and parasitic diseases classified elsewhere - G02
  • Meningitis due to other and unspecified causes - G03
  • Intracranial and intraspinal abscess and granuloma - G06
  • Other inflammation of eyelid - H01
  • Blepharitis - H01.0
  • Conjunctivitis - H10
  • Disorders of globe - H44
  • Phlebitis and thrombophlebitis - I80
  • Acne - L70
  • Fever of other and unknown origin - R50
  • Certain early complications of trauma - T79
  • Resistance to antimicrobial drugs - Z16


    Pregnancy categories:

  • A - Australia
  • C - United States (Risk cannot be ruled out)


    Salts and other forms used as active pharmaceutical ingredients (API):

  • Chloramphenicol Base
  • Chloramphenicol Glycinate
  • Chloramphenicol Hemisuccinate Acid
  • Chloramphenicol Hydrogen Succinate
  • Chloramphenicol Levogyre
  • Chloramphenicol Micronized
  • Chloramphenicol Palmitate
  • Chloramphenicol Palmitoylglycolate
  • Chloramphenicol Sodium Hemisuccinate
  • Chloramphenicol Sodium Succinate
  • Chloramphenicol Steaglate
  • Chloramphenicol Stearate
  • Chloramphenicol Succinate


    Synonyms, international and chemical names:

  • Chlooramfenicol
  • Chlooramfenikol
  • Chloramfenikol
  • Chloramphenicol, D-
  • Chloramphenicole
  • Chloramphenicolum
  • Cloranfenicol
  • Chlornitromycin
  • Chloroamphenicol
  • Chloromycetin
  • Chloromycetny
  • Cloramfenicol
  • Cloramfenicolo
  • Cloramffenicol
  • Cloranfenicol
  • Cloranfenicolo
  • Cloroamfenicolo
  • D-(-)-Chloramphenicol
  • D-Chloramphenicol
  • D-Threo-(1R,2R)-1-p-Nitrophenyl-2-dichloroacetamido-1,3-propanediol
  • D-Threo-Chloramphenicol
  • D-Threo-N-(1,1'-Dihydroxy-1-p-nitrophenylisopropyl)dichloroacetamide
  • Hloramfenikol
  • Kloramfenikol
  • Kloramfenikoli
  • Kloranfenikol
  • Laevomycetinum
  • Levomicetina
  • Levomitsetin
  • Levomycetin


    Brands, generics, trade names in various countries:

  • Brochlor - Sanofi-Aventis
  • Chemicetina - Fournier; AstraZeneca; Inde Farma Comercial
  • Chloramex - Aspen Pharmacare; Actavis; Averroes Pharmaceuticals
  • Chloramphenicol - Alcon; Hovid; IVAX; Pascual Laboratories; Sanofi-Aventis
  • Chloraxin - Cipla
  • Chlorcol - Adcock Ingram
  • Chlorocid - Egis
  • Chloromycetin - Pfizer
  • Chloroptic - Allergan; Tradis-Gat
  • Chlorsig - GlaxoSmithKline; Firma Popular; Pharmaco; Sigma Pharmaceuticals; Treasure Mountain Development; Zenaust Pharma
  • Cloramphenicol - DNA Pharmaceuticals; Quapharco; Tipharco
  • Cloraxin - F.T. Pharma; Nadyphar
  • Clorocil - Edol
  • Cogetine - General Drugs House
  • Colsancetine - Sanbe Farma
  • Dexoren - Indoco Remedies
  • Enclor - Idaman Pharma; Apotheca Marketing; Mcneil & Argus Pharmaceuticals
  • Farmicetina - Darrow Laboratorios; Rontag Laboratorios
  • Fenicol - Alcon; Sandoz
  • Fenizzard - Pizzard Laboratorios
  • Globenicol - Yamanouchi
  • Isopto Fenicol - Alcon
  • Kalmicetine - Kalbe Farma
  • Kemicetine - Pfizer
  • Levomycetin - Biosynthesis; Mapichem; Pharmstandard
  • Medoptic - Ashford Pharmaceutical Laboratories; Medilife Pharma
  • Minims Chloramphenicol - Chauvin Pharmaceuticals; Apex Pharma; Bausch and Lomb; Pan-Malayan Pharmaceuticals
  • Optichlor - Ashford Pharmaceutical Laboratories; F.P. Marketing
  • Optomycin - Optopics Laboratories; Metro Drug Distribution; Vendiz Pharmaceuticals
  • Paraxin - Roche; Nicholas Piramal
  • Pentamycetin - Sandoz; Sabex
  • Posifenicol C - Ursapharm Arzneimittel
  • Quemicetina - Pfizer; Rontag Laboratorios
  • Servicol - Novartis; Sandoz; Servipharm; Zuellig Pharma
  • Sificetina - Societa Industria Farmaceutica Italiana
  • Spersanicol - Novartis; Adcock Ingram; DKSH
  • Synthomycin - Biosynthesis; Farmaprim; Nizhpharm
  • Synthomycine - Teva; Rekah
  • Unison Ointment - Unison Laboratories
  • Vanmycetin - FDC
  • Xepanicol - Xepa-Soul Pattinson


    Pharmaceutical active ingredients used in medicine in combinations with chloramphenicol:

  • Amino Acids
  • Beclomethasone
  • Benzocaine
  • Betamethasone
  • Clotrimazole
  • Dexamethasone
  • Hydrocortisone
  • Lidocaine
  • Methyluracil
  • Neomycin
  • Phenylephrine
  • Polymyxin B
  • Prednisolone
  • Sulfacetamide
  • Tetrahydrozoline


    Some other medications in the same pharmacological classes:

  • Abelcet (Amphotericin B)
  • Aknemycin (Erythromycin)
  • Albucid (Sulfacetamide)
  • Altabax (Retapamulin)
  • Amikin (Amikacin)
  • Bacitin (Bacitracin)
  • Cleocin (Clindamycin)
  • Fluimucil Antibiotic (Thiamphenicol)
  • Fucidin (Fusidic Acid)
  • Garamycin (Gentamicin)
  • Hydrotricine (Tyrothricin)
  • Mecloderm (Meclocycline)
  • Montricin (Mepartricin)
  • Muprin (Mupirocin)
  • Mycifradin (Neomycin)
  • Mycostatin (Nystatin)
  • Nadoxin (Nadifloxacin)
  • Pentacin (Pentamycin)
  • Pimafucin (Natamycin)
  • RedActiv (Rifaximin)
  • Staphylomycine (Virginiamycin)
  • Terramycin (Oxytetracycline)
  • Tricomicin (Hachimycin)
  • Uticillin (Carfecillin)
  • Vanobid (Candicidin)


    Here is a list of popular medications containing chloramphenicol as a main active pharmaceutical ingredient; their trade names, forms, doses, companies - manufacturers, distributors, suppliers, researchers and developers:

    Trade name of the drug Pharmaceutical forms and doses Companies
    Chloromycetin
  • Capsules; Oral; Chloramphenicol 250 mg
  • Capsules; Oral; Chloramphenicol 500 mg
  • Cream; Topical; Chloramphenicol 1%
  • Drops; Ophthalmic; Chloramphenicol 0.5%
  • Drops; Otic; Chloramphenicol 0.5%
  • Drops; Otic; Chloramphenicol 5%
  • Injectable; Injection; Chloramphenicol Sodium Succinate 1 g
  • Ointment; Ophthalmic; Chloramphenicol 1%
  • Suspension; Oral; Chloramphenicol Palmitate 125 mg / 5 ml
  • Suspension; Oral; Chloramphenicol Palmitate 250 mg / 5 ml
  • Tablets; Oral; Chloramphenicol 50 mg
  • Tablets; Oral; Chloramphenicol 250 mg
  • Pfizer
  • Allphar Services
  • Amdipharm Mercury International
  • Daiichi Sankyo
  • Elea Laboratorio
  • ERFA
  • Goldshield Pharmaceuticals
  • King Pharmaceuticals
  • Parkedale Pharmaceuticals
  • Parke-Davis
  • Warner Chilcott
  • Warner Lambert
  • Zoetis
  • Zuellig Pharma
  • Kemicetine
  • Capsules; Oral; Chloramphenicol 250 mg
  • Drops; Ophthalmic; Chloramphenicol 0.5%
  • Ointment; Ophthalmic; Chloramphenicol 1%
  • Ointment; Ophthalmic; Chloramphenicol 2%
  • Pessaries; Vaginal; Chloramphenicol 500 mg
  • Solution; Otic; Chloramphenicol 1%
  • Pfizer
  • Kalbe Farma
  • Mac Laboratories
  • Primal Chemical
  • Zuellig Pharma
  • Levomycetin
  • Tablets; Oral; Chloramphenicol 250 mg
  • Tablets; Oral; Chloramphenicol 500 mg
  • Avexima
  • Xepanicol
  • Capsules; Oral; Chloramphenicol 250 mg
  • Drops; Ophthalmic; Chloramphenicol 0.5%
  • Xepa-Soul Pattinson
  • Apex Pharma Marketing
  • Four Star
  • FP Healthcare
  • Grafton Pharmasia
  • Metiska Farma
  • Tack Fung Medical Supplies
  • U.S. Summit



  • References:

  • PubChem database with main scientific information about active pharmaceutical ingredients : https://pubchem.ncbi.nlm.nih.gov/
  • PubMed database on US National Library of Medicine, National Institutes of Health: https://www.ncbi.nlm.nih.gov/pubmed/
  • DrugBank database containing information on drugs and drug targets: https://www.drugbank.ca/
  • MedlinePlus - an online information service produced by the United States National Library of Medicine: https://medlineplus.gov/
  • WebMD - an online publisher of news and information pertaining to human health and well-being: https://www.webmd.com/
  • Medscape - a website providing access to medical information for physicians and health professionals: https://www.medscape.com/
  • DailyMed drug labels resource from U.S. National Library of Medicine: https://dailymed.nlm.nih.gov/dailymed/spl-resources-all-drug-labels.cfm
  • Mayo Clinic - a nonprofit academic medical center focused on integrated clinical practice, education, and research: https://www.mayoclinic.org/
  • Drugs@FDA: U.S. Food and Drug Administration approved drug products database: https://www.accessdata.fda.gov/scripts/cder/daf/
  • Drug Product Database online query from Health Canada: https://health-products.canada.ca/dpd-bdpp/index-eng.jsp
  • European Medicines Agency (EMA) website with "Search for medicines" tool for European Union countries: https://www.ema.europa.eu/en
  • UK drug database from electronic Medicines Compendium (eMC): https://www.medicines.org.uk/emc
  • Australian medicine finder from NPS MedicineWise: https://www.nps.org.au/medicine-finder
  • Agencia Espanola de Medicamentos y Productos Sanitarios - AEMPS: https://www.aemps.gob.es/
  • Pharma and medical DB in EU on CBG-MEB: https://www.cbg-meb.nl/
  • Huge database for drug search especially for european and Latin America region: https://www.vademecum.es/equivalencia
  • MyHealthbox - multilanguage search engine for official information on medicines and healthcare products: https://myhealthbox.eu/en/
  • Pharmaceutical and other healthcare databases in some countries, primarily across Asia Pacific: https://www.mims.com/
  • MIMS drug index in China: http://www.mims.com.cn/china/drug/index/
  • IndiaMart - Various exploring tools, including for medical and pharmaceutical products in India: https://dir.indiamart.com/
  • A to Z brands and generics with their comparative prices on MedGuideIndia: http://www.medguideindia.com/show_generics.php
  • Generic drugs with their brand names on Medindia: https://www.medindia.net/drug-price/index.asp
  • Online Drug Information System, primarily for India and Pakistan: http://www.druginfosys.com/
  • Medizzine - hispanic portal for medicines: http://www.medizzine.com/pacientes/medicamentos/index.php
  • English version of Medizzine - health & medicines portal: http://www.medizzine.com/en/patients/drugs/index.php
  • Search tools for medications on Japanese Orange Book: http://www.jp-orangebook.gr.jp/cgi-bin/search/search_e.cgi
  • South Korean PharmaLink gateway: http://www.pharmalink.kr/
  • Medicines brand and generic index for Africa region: https://daktariafrica.com/medicine/raw/index/
  • APIs database on Galinos: https://www.galinos.gr/web/drugs/main/substances
  • RLSNet index for drugs, nutritions and supplements in Russia, Eastern Europe and Middle Asia regions: https://www.rlsnet.ru/tn_alf.htm
  • Taiwan Food and Drug Administration: https://www.fda.gov.tw/TC/index.aspx
  • Online medicine information directory from MedEx: https://medex.com.bd/generics/
  • The Anatomical Therapeutic Chemical ATC/DDD Index 2019: https://www.whocc.no/atc_ddd_index/
  • International Statistical Classification of Diseases and Related Health Problems 10th Revision, WHO: https://www.icd10data.com/

    Updated: September, 2019



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